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Dose de-escalation

Nevens et al.

Radiother Oncol

2017:Mar 22.

233 patients (3 prospective clinical trials):

SCC of head-and-neck

IMRT

±

concurrent chemo

Elective neck irradiation:

40 Gy (EQD2Gy)

Median follow-up 26 months

Regional control 89.2% at 2 years

Isolated regional recurrence in the “elective” neck 1/233 pts (0.4%)

Recurrence rates in the “elective” neck 3.9% at 2 years