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Biophysics in the Understanding, Diagnosis, and Treatment of Infectious Diseases Program

7

16:30 – 17:10

Alex Sigal, KwaZulu-Natal Research Institute for Tuberculosis and HIV,

South Africa

Mycobacterium Tuberculosis Growth in Dead Infected Cells Results in a Positive

Feedback Loop Driving Additional Cycles of Host Cell Death

17:10 – 17:30

Holger Gohlke, Heinrich-Heine-University Duesseldorf, Germany*

Complex Long-Distance Effects of Mutations that Confer Linezolid Resistance in

the Large Ribosomal Subunit

17:30 – 19:30

Poster Session III

Old Wine Cellar

Friday, November 20, 2015

8:00 – 12:00

Information

Auditorium Foyer

Session VIII

Chair: Wolf-Dieter Schubert, University of Pretoria, South Africa

8:30 – 9:10

Musa Mhlanga, CSIR Biosciences, South Africa

Super Resolution Microscopy Reveals a Preformed NEMO Lattice Structure that

is Collapsed in a Genetic Disease

9:10 – 9:50

Cheryl Arrowsmith, University of Toronto, Canada

Open Access Chemical Probes of Chromatin Regulators

9:50 – 10:10

Mintu Chandra, Indian Institute of Science Education and Research, Bhopal, India*

Insights into Molecular Switch: Crystal Structure Analysis of Wild Type and Fast

Hydrolyzing Mutant of EhRabX3, a Tandem Ras Superfamily GTPase from

Entamoeba Histolytica

10:10 – 10:40

Coffee Break

10:40 – 11:20

Timothy Wells, Medicines for Malaria Venture, Switzerland

Moving Forward New Medicines and New Targets in Malaria

11:20 – 12:00

Michael Starnbach, Harvard Medical School, USA

Bacterial Manipulations of the Host Cell Proteome

12:00 – 12:40

Bryan Trevor Sewell, University of Cape Town, South Africa

On the Mechanism of the Amidases – Consequences for Sulfhydryl Catalysis and

Drug Design

12:40 – 13:00

Closing Remarks and

Biophysical Journal

Poster Awards

*Short talks selected from among submitted abstracts