

TABLE OF CONTENTS
Selected Recent Materials - Reproduced in this Study Guide
2016 SECTION 5: RHINOLOGY AND ALLERGIC DISORDERS
ADDITIONAL REFERENCE MATERIAL………………………………………….i-vi
I.
Rhinology
A.
Olfaction
Henkin RI, Schultz M, Minnick-Poppe L. Intranasal theophylline treatment of hyposmia and
hypogeusia: a pilot study.
Arch Otolaryngol Head Neck Surg
. 2012; 138(11):1064-1070. EBM
level 2............................................................................................................................................1-7
Summary
: This is an open-label study designed to determine whether intranasal theophylline methylpropyl
paraben can correct hyposmia and hypogeusia. In a cohort of ten patients, oral theophylline treatment
improved taste and smell acuity in six patients after 2 to 12 months of treatment. Intranasal theophylline
treatment improved taste and smell acuity in eight patients after 4 weeks, with improvement greater than
after oral administration.
B.
Nasal Cavity
1.
Septum, turbinates, empty nose
Leong SC. The clinical efficacy of surgical interventions for empty nose syndrome: a
systematic review.
Laryngoscope
. 2015; 125(7):1557-1562. EBM level 3.......................8-13
Summary
: Leong presents a systematic review of prior studies evaluating surgical outcomes for empty
nose syndrome.
C.
Paranasal Sinuses
1.
Diagnosis
a.
Imaging
Garneau J, Ramirez M, Armato SG 3rd, et al. Computer-assisted staging of chronic
rhinosinusitis correlates with symptoms.
Int Forum Allergy Rhinol
. 2015; 5(7):637-642.
EBM level 3................................................................................................................14-19
Summary
: This study presents a modification of the Lund-Mackay (LM) system. Each sinus is
still scored on a scale of 0 to 2. However, partial opacification in each sinus is quantified by
volume using a computer-based algorithm and then assigned a score from 0 to 2. Unlike the
conventional LM score, the modified LM system had correlation with symptoms measured by the
total nasal symptom scores.
b.
Guidelines
Brietzke SE, Shin JJ, Choi S, et al. Clinical consensus statement: pediatric chronic
rhinosinusitis.
Otolaryngol Head Neck Surg
. 2014; 151(4):542-553. EBM
level 3..........................................................................................................................20-31
Summary
: This article presents the clinical consensus statement for pediatric chronic sinusitis
diagnosis and management from the American Academy of Otolaryngology–Head & Neck
Surgery Foundation.