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Adulteration of Dietary Supplements
with Synthetic PDE5 Inhibitors
•
Serious problem
i l
i
d (
l h l) h l h ff
–
Potent a ser ous a verse even et a ea t a ects
–
Adulteration with approved drugs but also their
unapproved analogs (unknown toxicological effects)
–
High incidence of adulteration
Campbell
et al
.,
J. Sex. Med.
10 (2013) 1842‐1849:
‐
81%
out of 91 tested
herbal products adulterated
with synthetic PDE5 inhibitors and their analogs