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PHYSIOLOGICAL IMAGING
MRI SPECTROSCOPY
NAA
: marker of neural integrity
Choline
: membrane turnover
Creatine: energetic
Myoinositol
: astrocytic marker
Lipid
: tissue destruction/necrosis marker
Lactate: hypoxia marker
Glutamine and Glutamate: excitatory markers
High choline correlate with high tumor
proliferative index
Pitfalls
: - min 1 cm3 voxel size
- not suitable for posterior fossa lesions and lesion
- common aspecific spectral findings