EP and chemotherapy
Number of patients
N=19
Age
3-14 years (median, 7.5 years)
Regimen
carboplatin, 560 mg/m2, with vincristine,
1.5 mg/m2, weekly for 3 weeks,
alternating at 4-week intervals with
ifosfamide, 1.8 g/m2, and etoposide, 100
mg/m2, for 5 consecutive days for a total
of 4 cycles
5 years PFS
74%
Prognostic factors
The extent of surgical resection was not a
significant prognostic factor in this study
PD with non-R0
20%
03/01/13
Cancer.1997 Jul 15;80(2):341-7.
Adjuvant chemotherapy for the treatment of intracranial ependymoma of childhood.
Needle MN1
,
Goldwein JW,
Grass J , Cnaan A , Bergman I,
Molloy P,
Sutton L,
Zhao H , Garvin JH Jr , Phillips PC.