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EP and chemotherapy

Number of patients

N=19

Age

3-14 years (median, 7.5 years)

Regimen

carboplatin, 560 mg/m2, with vincristine,

1.5 mg/m2, weekly for 3 weeks,

alternating at 4-week intervals with

ifosfamide, 1.8 g/m2, and etoposide, 100

mg/m2, for 5 consecutive days for a total

of 4 cycles

5 years PFS

74%

Prognostic factors

The extent of surgical resection was not a

significant prognostic factor in this study

PD with non-R0

20%

03/01/13

Cancer.

1997 Jul 15;80(2):341-7.

Adjuvant chemotherapy for the treatment of intracranial ependymoma of childhood.

Needle MN

1

,

Goldwein JW

,

Grass J , Cnaan A , Bergman I

,

Molloy P

,

Sutton L

,

Zhao H , Garvin JH Jr , Phillips PC

.