677 / 1266
HFRT for DIPG
Toxicity included intralesional necrosis and steroid
dependency at the intermediate and highest dose
levels, as well as vascular events in a small # of pts
treated at the highest dose levels
Doses as high as 78 Gy did not result in any significant
improvement in time to progression, MST, or survival
at 1 and 2 yrs