Children’s Cancer Group 945
131 patients with a diagnosis of AA or GBM
•
Surgery biopsy (<10% resection)
•
Partial resection (10-50%)
•
Subtotal resection (50-90%)
•
Radical (90%)
PFS at 5 years rate of 35% in radical resection compared with 17% in
subtotal resection (p= 0.006)
AAs
PFS at 5 years 44% in radical vs. 22% in subtotal (p= 0.055)
GMB
PFS at 5 years rate of 26% in radical vs. 4% in subtotal (p= 0.046)
Wisoff et al. J Neurosurg 1998
Surgery