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cholesteatoma when taken to the operating room, and

none had residual cholesteatoma.

There were three (3.8%) CWU patients who had a

complication following their first tympanoplasty-

mastoidectomy, including postoperative nausea and vom-

iting requiring admission, a tegmen defect with cerebro-

spinal fluid leak, and a surgical site infection. For CWU

patients undergoing a second-look procedure, two (4.3%)

patients experienced a complication including encephalo-

cele and a wound seroma.

For the purposes of assessing the audiology outcomes,

CWU patients were grouped into second-look and no

second-look cohorts. When examining WRSs and ABGs at

pre-, immediate postoperative, and the latest follow-up vis-

its, there were no significant differences observed (Table I)

(

P

>

0.05 for all variable pairs). In all CWU patients, no

OCR was completed in 42 (52.5%) patients. Seven (8.8%)

patients had OCR at a planned single-stage procedure and

31 (38.8%) at a planned second-look procedure. The pre-

and posttreatment air conduction pure tone average and

WRS results for all CWU patients are reported in supple-

mental figures (Figs. 1 and 2, respectively).

Charges and costs for the components of care were

tabulated (Table II). The most expensive charge component

was the surgical procedure, followed by the CT scan of the

temporal bones. A cost analysis demonstrated that

patients with a second-look strategy had a significantly

higher number of postoperative visits compared to patients

with no second look (10.4 visits vs. 6.32;

P

5

0.0007)

(Table III). There was no significant difference in follow-up

period, temporal bone CTs, and audiology clinic visits

(each

P

>

0.05). Canal wall-up procedures patients with a

second-look management strategy had a significantly

higher cost of care versus patients with no second-look

strategy (USD mean of $41,411 vs. $23,529;

P

<

0.0001).

DISCUSSION

The primary goal of cholesteatoma surgical manage-

ment is to produce a safe ear, with a secondary goal to

TABLE I.

Audiometric Outcomes for CWU Patients Who Underwent Either Second Look or No Second-Look Operative Strategy.

Mean (CI 95%)

No Second Look

Second Look

P

Value*

Preoperative air bone gap

21.2

(16.8–25.6)

26.4

(22.8–30.1)

0.07

Preoperative WRS

85.0

(77.9–92.0)

92.8

(86.5–99.1)

0.10

Postoperative air bone gap

21.7 (17.1–26.2)

27.0 (23.2–30.8)

0.08

Postoperative WRS

83.2 (75.2–91.3)

91.0 (84.2–97.9)

0.14

Most recent air bone gap

23.7

(18.3–29.1)

28.2

(23.7–32.7)

0.21

Most recent WRS

85.8

(77.1–94.5)

90.5

(83.7–97.2)

0.40

WRS change preoperative to postoperative

2

4.58 (

2

12.2–3.07)

2

1.87 (

2

8.71–4.98)

0.60

WRS change postoperative latest

2

2.48 (

2

8.87–3.91)

2

1.27 (

2

6.61–4.08)

0.77

WRS change preoperative latest

2

2.86 (

2

10.89–5.17)

2

3.16(

2

9.77–3.45)

0.95

*One-way ANOVA. Two-tailed.

ANOVA

5

analysis of variance; CI

5

confidence interval; CWU

5

canal wall-up procedures; WRS

5

word recognition score.

Fig. 1. Pretreatment pure tone average and word recognition

score scattergram.

Fig. 2. Posttreatment pure tone average and word recognition

score scattergram.

Crowson et al.: Second-Look Tympanoplasty-Mastoidectomy

101