130 / 264
TABLE II.
Results of Studies Comparing Disease Recidivism Rates Between the CWU Technique and the CWD Technique.
Article
Study Population
Residual/Recurrent Risk
No. of Ears*
CWU/CWD
Follow-up
(mean, yr.)
Age
Range (yr.)
CWU No. (%)
CWD No. (%)
Absolute Risk
Reduction %
(95% CI)
P
Value
Relative Risk
(95 % CI)
Palmgren (1979)
20
194
50/144
9.4
n/a
†
n/a (15)
(6%)
9 (n/a)
NS
‡
2.5 (n/a)
Brown (1982)
6
1044
628/416
10
15 to 75 214 (34.1)
54 (13)
21 (16 to 26%)
<
.001
2.6 (2.0 to 3.4)
Roden (1996)
18
97
54/43
0.5 to 5 19 to 85
11 (20.4)
2 (4.7)
16 (3 to 28%)
.03
4.4 (1.0 to 18.7)
Nyrop (1997)
7
58
41/17
10
15 to 77
25 (61.0)
0 (0)
61 (46 to 76%)
<
.001
n/a
Ajalloueyan (2006)
19
108
36/72
10
16 to 81
6 (16.7)
4 (5.6)
11 (
2
2 to 24%)
.08
3.0 (0.9 to 10.0)
Stankovic (2007)
15
658
360/298
3
>
16
28 (7.8)
66 (22.1)
2
14 (
2
20 to
2
9%)
<
.001 0.35 (0.23 to 0.53)
Declerck (2010)
4
2nd look
88
74/14
1 to 1.2 18 to 84
19 (25.7)
0 (0)
26 (16 to 36%)
.03
n/a
Total
165
117/48
2.5
18 to 84
21(18.9)
§
0 (0)
19 (12 to 26%)
.001
n/a
*Adult cases only.
†
No exact age range reported. Mean ages for the youngest 50 and the oldest 50 patients: 21 and 55 years, respectively.
‡
No exact patient numbers reported.
§
111 patients had follow-up.
CI
5
confidence interval; CWD
5
canal wall down; CWU
5
canal wall up; No.
5
number; n/a
5
not available/applicable; NS
5
not significant; yr.
5
year.
TABLE III.
Outcomes of Studies Comparing the CWU Technique and the CWD Technique and Making a Distinction Between Residual and Recurrent Disease Rates.
Article
No.*
CWU/ CWD FU (mo.)
CWU Technique No. (%)
CWD Technique No. (%)
Risk Difference (95% CI)
Relative Risk (95% CI)
Residual
Recurrent
Residual
Recurrent
Residual
Recurrent
Residual
Recurrent
Roden (1996)
18
97
54/43
6 to 60 11 (20.4%)
0 (0%)
2 (4.7%)
0 (0%)
16% (3 to 28%)
0% (0%)
4.4 (1.0 to 8.7)
n/a
Stankovic (2007)
15
658 360/298
36
11 (3.1%)
17 (4.7%)
21 (7.0%)
45 (15.1%)
2
4% (
2
7 to 1%)
2
10% (
2
15 to 6%)
0.43
(0.21 to 0.88)
0.31
(0.18 to 0.53)
Declerck (2010)
4
2nd look
88
74/14 CWU: 12
CWD: 14
13 (17.6%)
6 (8.1%)
0 (0%)
0 (0%)
18% (9 to 26%)
8% (2 to 14%)
n/a
n/a
CI
5
confidence interval; CWD
5
canal wall down; CWU
5
canal wall up; FU
5
follow-up; mo.
5
months; No.
5
Number; n/a
5
not available/applicable; No.*
5
number of operated ears.
Laryngoscope 126: April 2016
Kerckhoffs et al.: A Review on Cholesteatoma Recidivism After CWU and CWD
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