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ESTRO IG and Adaptive

Course Parikh Budapest 2018

Dutch Trial

van Gijn et al, Lancet Oncol 2011

1861 patients with

resectable rectal

cancer

randomized:

TME alone vs

25 Gy / 5 fx preop

If surgery alone, postop RT

required for SM ≤ 1mm

10 year LR 11 vs 5%

favoring preop RT

No difference in OS

LR