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Established need for radiotherapy image

guidance and adaptation

8

CTV+0.5 CTV+1.0 CTV+1.5 CTV+2.0 CTV+2.5

Skin

0

19

56

93

96

Bone

0

41

63

89

96

Soft tissue

52

89

96

100

100

Foroudi et al. Bladder cancer radiotherapy margins: a comparison of daily alignment using skin, bone or soft tissue

2012 Clin Oncol 24 673-681

Retrospective analysis of 27 patients having daily CBCT

To determine CTV to PTV margin required to achieve coverage of bladder

when using skin, bone or soft tissue matching

% of patients where expanded CTV covered 95% of wall displacements