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Radiotherapy

Early Breast Cancer: S

±

XRT meta-analysis

EBCT Collaborative Group. Lancet 2000

Total: 40 Prosp. Rand. Trials, N ≈ 20,000 (50% had N+ve disease),

XRT treating breast/chest wall, SCF, AX, IM regions

Difference = 4.8%

Increased mortality

with XRT !

- 30% Cardeiac

deaths