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Intra-fractional stability

Study

Immobilization

system

Imaging modality

Intrafractional error

3D vector

Boda-Heggemann

2006

Thermoplastic masks

Scotch cast mask

Cone-beam CT

1.8mm

±

0.7mm

1.3mm

±

1.4mm

Masi 2008

Thermoplastic mask & Bite block

Bite-block

Cone-beam CT

< 1mm

< 1mm

Lamda 2009

BrainLab mask

Orthogonal x-rays

0.5mm

±

0.3mm

Ramakrishna 2010

BrainLab mask

Orthogonal x-rays

0.7mm

±

0.5mm

Guckenberger

Scotch cast mask

Thermoplastic masks

Cone-beam CT

0.8mm

±

0.4mm

0.8mm

±

0.5mm

Intra-fractional uncertainties in frame-less IGRT

Intra-fractional uncertainties of ~ 1mm need to be

considered in non-invasive frame-less IGRT