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ESTRO IG and Adaptive

Course Parikh 25.10.2016

CTV, PTV margins for APBI:

Brachytherapy (Mammosite, SAVI):

Cavity + 1 cm = CTV = PTV

EBRT:

Cavity + 1-1.5 cm = CTV.

CTV + 1 cm = PTV

PTV = Cavity + 2-2.5 cm

Larger PTV margins needed due to:

Setup uncertainty

Intra-fraction motion

We sought to evaluate MR-IGRT for delivery of APBI given easy

localization of cavity on MRI (setup) and ability to monitor intra-

fraction motion.

Background

Cavity

Preferred

Alternative

CTV=Br PTV

EBRT PTV

Courtesy of Maria Thomas, MD, PhD

MRG-RT: Moderate Experience - Breast