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Tumor minimum dose

1 2 3 4 5 6 7 8 9 10

-10%

-5%

0%

5%

10%

relative difference min dose GTV

patient

accumulated on midV vs on 4D dose

mean = 0.03%

Conventional

On-line Hypo

Mexner et al. IJROBP 2008

ESTRO IGRT 2015