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Cervix cancer =

on-line adaptive vs population-based margin

Bladder-based ITV

(Margin 38mm)

vs

Adaptive strategy

(library of plans

based on 10 pretreatment

CT + after 40Gy with

varying bladder filling

)

(Margin 7-10mm)

volume reduction

PTV : 48%

Bladder 5to 45%

Rectum 26% to 74%

03/01/13

Bondar M et al., IJROBP 2012