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PET in-vivo

• On-line and off-line

• 5 min on-line to 30 min off-line

imaging time

• Measure activity, not dose

• Suffers from biological wash-out

and low counting statistics

• Clinically applied. 1–2 mm

accuracy in favorable locations

Prompt gamma imaging

• On-line

• Especially suitable for beam range

• Indirect measurement, not dose

• Immediate measurement

• Early stage of development

Range Verification: PET

Courtesy of Martijn Engelsman