54-55 / 3581
Early Breast Cancer: S ± XRT meta-analysis
Total: 40 Prosp. Rand. Trials, N ≈ 20,000 (50% had N+ve disease),
XRT treating breast/chest wall, SCF, AX, IM regions
Radiotherapy
EBCT Collaborative Group. Lancet 2000
Difference = 4.8%
Increased mortality
with XRT !
- 30% Cardiac
deaths