676-677 / 3581
Daily IG-IMRT and reduced PTV margin in clinical practice
•
2001-2007
•
Daily IG-IMRT
•
Median dose 78 Gy (74-78Gy @ 2Gy/fx)
•
165 pts
•
PTV margin10mm (n= 78) vs. 5mm (n= 87)
•
Median FU = 39 months
•
GI : G2 = 1.2% (5mm) vs. 2.6% (10mm) , p = NS
•
NoG3+
Logrank test : p=0.576
0.00
0.25
0.50
0.75
1.00
Survival(%)
83 81 81 76 64 58 46 28 24 22 19 13 8
10 mm
87 86 85 79 63 56 44 36 30 19 14 5 3
5 mm
N at risk
0 6 12 18 24 30 36 42 48 54 60 66 72
Months
5 mm
10 mm
Biochemical Progression-free Survival
Créhange G. et al., Radiother Oncol 2012