AOAC SPIFAN ERP Meeting Book (3-16-16)

Additional data on Multi-Laboratory Validation – Vitamin C method AOAC First

Action 2012.22 / F. Martin, NRC/AS

23.Nov.2015

CONFIDENTIAL

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Page 2 / 9

B A C K G R O U D

Multi-Laboratory Testing (MLT) data on SPIFAN matrices for First Action method AOAC 2012.22

“Vitamin C (ascorbic acid) in Infant Formula and Adult/Pediatric Nutritional Formula by UHPLC-UV”

was sent to the Expert Review Panel (ERP) in January 2015

Based on the aforementioned data, the method was not recommended to move forward to Final

Action status due to high reproducibility values obtained for two samples (Infant Formula RTF Milk

Based and Adult Nutritional Powder Low Fat).

The Expert Review Panel offered the method authors the opportunity to test fresh samples from the

new SPIFAN kit. An additional MLT testing on these two matrices was thus organized. The aim of this

document is to present the results obtained on these two fresh samples.

RDLS-RD50006 Multi Laboratory Test – AOAC First Action Method 2012.22 Ascorbic Acid (Vitamin C) in Infant Formula and

Adult/Pediatric Nutritionals, January 16

, 2015.

2012.22/VitC-03 (February 2016) - MLT

FOR ERP USE ONLY

DO NOT DISTRIBUTE