1196 / 1544
0,0
200,0
400,0
600,0
800,0
1000,0
1200,0
1400,0
1600,0
1800,0
0,0 10,0 20,0 30,0 40,0 50,0 60,0
Gy
cc
Black: pts with tox
Grey: pts without tox
UVA: V15 best predictor
compared to V40-
V50…..due to larger
differences at low doses
(geometry…no biology !!!!)
V15 AS A SURROGATE OF THE HIGH-DOSE REGION IN
THE BOX TECHNIQUE
NO BIOLOGICAL MEANING - DONT USE IT (ALONE) IN
IMRT OPTIMIZATION…