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Computer treatment planning systems (TPS), inverse planning approaches and

optimizer algorithms were in their early days

➔

Dependence on another new technology at that time, the multi-leaf collimator

(MLC), which was initially designed to replace cerobend blocks

“A handful of research oriented centers developed their own

custom build solution of

rotational therapy solutions

(IMAT, …).”

-William Beaumont Hospital group, USA, C. Yu et al.

-UZ Gent, Belgium, De Neve et al.

-…

Issues with early solutions