First analysis of data from phase 3 randomised trials comparing SABR with surgery
First report to
suggest that SABR is better tolerated and might lead to better
OS
compared to surgery for operable clinical stage I NSCLC
Results are compatible with the notion that the two therapies are equally effective
with lower survival after surgery possibly resulting from comorbidities worsened by
the surgical reduction of lung function
Small patients sample size and short follow-up
BUT…
These findings nevertheless
strongly suggest at least equipoise
between the
two modalities and support the
initiation of larger randomised studies
to
validate these findings