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First analysis of data from phase 3 randomised trials comparing SABR with surgery

First report to

suggest that SABR is better tolerated and might lead to better

OS

compared to surgery for operable clinical stage I NSCLC

Results are compatible with the notion that the two therapies are equally effective

with lower survival after surgery possibly resulting from comorbidities worsened by

the surgical reduction of lung function

Small patients sample size and short follow-up

BUT…

These findings nevertheless

strongly suggest at least equipoise

between the

two modalities and support the

initiation of larger randomised studies

to

validate these findings