Frameless vs. Invasive frame-based
50
Invasive frame-based: Submillimeter accuracy??
Good immobilization
Frameless approach: Submillimeter accuracy!!!
Immobilization?
Framebased
SRS
Frameless
IGRT
Positioning error
(3D)
0,5 – 1,5 mm
< 1 mm
Intrafractional
error (3D)
< 1 mm
< 1,5 mm
Maciunas 1994
Lamba 2009
Ramakrishna 2010
Murphy 2003
Boda-Heggemann 2006
Guckenberger 2007
Lamba 2009
Ramakrishna 2010
Gevaert 2012