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Frameless vs. Invasive frame-based

50

Invasive frame-based: Submillimeter accuracy??

Good immobilization

Frameless approach: Submillimeter accuracy!!!

Immobilization?

Framebased

SRS

Frameless

IGRT

Positioning error

(3D)

0,5 – 1,5 mm

< 1 mm

Intrafractional

error (3D)

< 1 mm

< 1,5 mm

Maciunas 1994

Lamba 2009

Ramakrishna 2010

Murphy 2003

Boda-Heggemann 2006

Guckenberger 2007

Lamba 2009

Ramakrishna 2010

Gevaert 2012