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ESTRO IMRT course 2015
IMRT optimization: algorithms&cost functions
Brussels October 5th, 2015
-12-
(Dose
target
)
(Dose
OAR
)
The IMRT optimization problem:
What is optimized, and what are the variables?
(2) optimize a weighted sum
of these CFs by finding an
optimal fluence modulation
pattern for the beams
(1) the treatment/dose goals
are expressed in terms of
C
ost
F
unction(s) for target
and OARs.
CF
target
CF
OAR
The optimization
variables may be
beamlet weights
or
segment weights and
-shapes
=> depending on the
case, in the order of
10
3
-10
4
variables!