567 / 1544
ESTRO IMRT course 2015
Adaptive Radiotherapy
Brussels October 8th, 2015
-24-
The Beaumont offline adaptive RT approach
Yan et al. 2000: An off-line strategy for constructing a patient-specific planning target volume
in adaptive treatment process for prostate cancer. IJROBP 48(1)
Martinez et al. 2001: Improvement in dose escalation using the process of adaptive
radiotherapy combined with three- dimensional conformal or intensity-modulated beams for
prostate cancer. IJROBP 50(5)
planning
CT
(IMRT)
plan
1 cm margin
around CTV
PI,
CT
…
Fx
5
Fx
1
…
Fx
6
estimation of
systematic setup
error
, characterization of
internal organ motion
new isocentre
new plan
Fx
N
…
PI,
CT
(IMRT)
plan
new, adapted
PTV: ‘cl-PTV’
First systematic clinical adaptive RT implementation
at Beaumont Hospital, Royal Oak, Michigan: since 1997!
this is why it is called
‘offline’
!