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Follow-up (median 54 months; range: 27-79

months)

3 locoregional

relapses

5-year:

97% LC

57% PFS

68% OS

MVA: R1 resection (p=0.03)

ypN2 disease (p=0.04)

UVA: adjuvant chemotherapy (p=0.04)

MVA: R1 resection (p=0.03)

ypN2 disease (p=0.04)

UVA: adjuvant chemotherapy (p=0.04)

ypT3-4 tumor (p=0.01)

Dworak grade 0-2 (p=0.03)

21

De Ridder and Engels et al, Int J Radiat Oncol Biol Phys and Radiother Oncol 2008 - 2014