Flipping Book

Eisbruch et al, IJROBP 45, 3:577, 1999

Prospective study

• 51 patients, parotid sparing bilateral neck RT

(advanced head & neck)

37 patients, unilateral neck RT (small lateral tumors)

• Saliva flow rates measured before and 1 year after RT

• Threshold mean dose to the glands for suppression of the salivary flow: 24 - 26

Roesink et al, IJROBP 51, 4:938, 2001

Prospective study

• 180 patients, 174 parotid glands

• Saliva flow rates measured before and after RT

(6 weeks, 6 months, 1 year)

• Postradiotherapy saliva flow decreased with increasing irradiated volume to a

mean dose between 35 and 45

• No threshold mean dose