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Patient History:

Male, 74 years old:

7/2009: primary disease: cT4N3M0, treated induction

chemo , consolidation RT

8/2010: metastatic disease: Tarceva

5/2012: progression of

solitary metastasis lower

left lobe

, RT 2x20 Gy

Delineation:

On 60% phase in stable exhale (

volume 4.30 ccm

)

Size: AP: 2.6 cm, CC: 2.2 cm, LR: 2.2 cm

Motion:

Visicoil marker 0.75 mm diameter, 10 mm length

Amplitude CC of 14mm p2p in 4D CT

PTV definition:

Tracking:

CTV=GTV,

PTV

TR

=CTV + 5mm isotropically

ITV backup plan:

ITV= sum CTV all phases + 5 mm isotropically

(for CBCT guidance)

PTV

ITV

=ITV+5mm isotropically

PTV

TR

= 18.3 ccm

,

PTV

ITV

=30.2

ccm

(39% PTV volume reduction)

Example ITV vs. Tracking approach