348
FIG. 11.15.
DCIS, micropapillary and cribriform.
A:
Prominent peripheral micropapillary arches with
secondary cribriform microlumina. (From Rosen PP. The pathology of breast carcinoma. In: Harris
JR, Hellman S, Henderson IC, Kinne DW, eds.
Breast diseases
. Philadelphia: J.B. Lippincott, 1987:150,
with permission.)
B:
Enlarged view of
(A)
showing low-grade nuclei.
C:
Large peripheral arcades
which encroach on the lumen that contains histiocytes. (From Rosen PP, Oberman HA.
Tumors of
the mammary gland.
(
AFIP Atlas of Tumor Pathology,
3rd series, vol. 7). Baltimore: American Reg-
istry of Pathology, 1993.)
D:
DCIS with a fully developed cribriform structure that can arise in the
patient with micropapillary DCIS.
FIG. 11.16.
DCIS, micropapillary.
A:
An example of relatively uncomplicated micropapillary DCIS
with apocrine cytology.
B:
Florid micropapillary DCIS with numerous epithelial fronds filling the
duct lumen.