Rosen's Breast Pathology, 4e - page 50

358
Chapter 11
FIG. 11.33. 
DCIS, “healing.”
A:
Prominent periductal fibrosis and chronic inflammation.
B,C:
Severe
periductal fibrosis with lymphocytic reaction. The epithelial element is relatively attenuated
(C)
.
D:
Scar composed of collagen and elastin fibers with calcifications at the site of “healed” DCIS. ­Images
(A–D)
are from a single specimen.
E:
Marked periductal fibrosis with residual necrotic DCIS.
F:
Concentric fibrosis forms a dense calcified scar with sclerosing entrapment of carcinoma cells.
Note periductal lymphovascular channel involvement by tumor cells. No invasive carcinoma was
­identified elsewhere in this case.
1...,40,41,42,43,44,45,46,47,48,49 51,52,53,54,55,56,57,58,59,60,...148
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