60-61 / 328
of GA and CS in Dietary Supplements
Submitted by:
Frantisek Kvasnicka,
University of Chemistry and Technology,
Prague
Official Methods
SM
status.
9/0/1 (Abstain:
Covance)
Secondary:
Curtis
Phinney
CHON-003
Title:
Chondroitin by IR and
Dimethylmethylene Blue (DMMB)
Spectrophotometry
Submitted by:
Xun Yan, Amway
Motion 1:
MOTION to not move CHON-003 to
First Action
Official Methods
SM
status.
Motion 2:
MOTION to ask the method author whether they can
provide additional data regarding the interfering
compounds that are listed on the SMPR008 and if
they have additional data for system suitability / all
validation data.
Motion 1:
Solyom/Spzylka
9/0/1 (Abstain:
Covance)
Motion 2:
Solyom/Hildreth
9/0/1 (Abstain:
Covance)
Primary:
Aniko Solyom
Secondary:
Nour Eddine
Es-Safi
CHON-004
Title:
Determination of Chondroitin
Sulfate Content in Raw Materials and
Dietary Supplements by High-
Performance Liquid Chromatography
with Ultraviolet Detection After
Enzymatic Hydrolysis
Submitted by:
David Ji, Analytical
Laboratories in Anaheim, Inc.
MOTION 1:
MOTION to move CHON-004 to First Action
Official
Methods
SM
status.
Motion 2:
MOTION to be considered for
Final Action
Official
Methods
SM
status, the author(s) should:
•
Optimize and control the moisture in the
chondroitin sulfate including appropriate
vessels and glassware.
•
Investigate alternative LC columns.
•
Optimize the LC conditions.
•
Look at lessons learned from USP.
•
Include a potency evaluation of the enzyme
use.
•
Investigate use of the USP standard that is
currently available.
•
Certified reference material recommended.
Motion 1:
Sullivan/Koerner,
8/0/2 (Abstain:
Covance, Hildreth)
Motion 2:
Sullivan/Reins
8/0/2 (Abstain:
Covance, Hildreth)
Primary:
Darryl
Sullivan
Secondary:
Phillip
Koerner
ERP PROFILE SUMMARIES
57