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Current Part 1
–
Interference testing
(false negatives)
–
Cross‐reactivity testing
(false positives)
Proposed revisions in
Part 2
•
Soil testing for robustness
against potential interferants
•
Soil testing for assay specificity
Reason 1: Soil testing aligns directly with
Part 1
Soil testing for interferants and cross‐
reactivity fits much better in Part 1 vs Part 2
on DNA testing
.
Reason 2: Soil testing should apply to all
SPADA SMPRs
•
Soil testing is relevant for non‐nucleic acid analytical
technologies (e.g., protein detection).
•
Current SMPRs for proteins omit Part 2 of the
Environmental Panel (e.g., SMPR 2016.011 for
Botulinum neurotoxins A1 and A2).
•
The introductory paragraph for the panel currently
states,
“Part 2 is not applicable to techniques that
do not detect nucleic acid.”
Moving soil testing to Part 1 would enable soil testing
to apply to all SMPRs, regardless of analytical
approach.