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Influence on the radiological pathlength

Moving anatomical districts with strong inhomogeneities may cause variation

in BP deposition

Particles stop before/beyond the expected position.

Uncorrect Dose Distribution

Particle Therapy

high sensitivity of the dose distribution to density variation

in the entrance channel

any concept to compensate for the uncertainties due

to organ motion/variation needs to incorporate also the influence on the beam’s

range on dose DEFORMATION