2192-2193 / 3107
Rate and efficiency of repair systems
• The estimated rate of single strand
DNA breaks and base loss is up to
10
4
/ cell / day
ONLY 30%!!! population develops cancer
• A human body (70 kg) is comprised of
10
14
cells
•
100.000.000.000.000
• The number of blood and small
intestinal cells produced per day is
10
10
–10
11
, respectively
Suit, H. Radiother & Oncol 2011