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Multiple initial imaging and CBCT

Outline VesicaART study

Planning CT on void bladder and back up plan with robust margins

Contour bladder on CBCT at the first 5 fractions and generate

PSV

Small

, encompassing the two smallest bladder volumes, PSV

Medium

, the

union of all five volumes, PSV

Large

, standard PTV margins

CBCT fraction 6-30, bony anatomy match

Clinical selection of the library plan with the smallest possible PSV

Using this technique PTV volumes were reduced by 30% on average

Vestergaard, Acta 2014