572-573 / 3107
Scientific evidence: 3 Randomized controlled trials
Study
Significant Endpoints
n IMRT Non-
IMRT
P-value
Donovan
R&O 2007
Change in breast
appearance
306 40% 58% 0,008
Breast
Evidence
25
(serial photographs)
Pignol
Breast 2008
Moist desquamation
351 31% 48% 0,002
Mukesh
JCO 2013
Teleangiectasia (grade 2-3)
Cosmesis (poor)
1145 8%
12%
14%
22%
0,02
0,03
(& comparative case studies)