L0_2016_Athens_Physics_Programme

Scientific evidence:

1 RCT; many comparative studies

Consistent results with :



↓ acute and late GI toxicity



=/↓ acute and = late GU toxicity



↑ biochemical control with dose-escalation

Prostate

Evidence

75.6 Gy

< 72 Gy

81 Gy IMRT

Zelefsky IJROBP 2008

Late Grade ≥2 rectal toxicities

1751 pts