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Park et al. IJROBP 82:e425-e431. 2012

Validating fiducial markers for IGRT for APBI

- in 26 patients 3-4 gold fiducial markers placed at the periphery of lumpectomy cavity

- free breathing 4D CTs were acquired pre- and posttreatment

- intrafraction motion, variations in respiratory motion and fiducial migration were calculated

end-inspiration

end-expiration

end-inspiration

end-expiration

fiducial markers are stable

throughout the course of APBI, no evidence of migration

planning target volume

margins

when using bony landmarks should be

10 mm

and can be

reduced to 6 mm if using fiducials