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The role of 4D-CT in APBI

Meattini al. Radiol Med doi 10.1007/s11547-015-0541-1. 2015

No significant differences

between PTV volumes, PTV coverage, OAR sparing and

centroid position were found when comparing 3D-CT and 4D-CT plans

Conventional

3D CT-based planning is adequate

for APBI

Comparison of PTVs between 3D-CT and 4D-CT plans

3D-CT 4D-CT

PTV

V95%

97

97

Heart

V3 (%)

5

5

Uninvold ips. breast V15 (%)

31.1

31.5

Contralat breast

V1 (%)

1.0

1.1

Ipsilat lung

V10 (%)

10.7

11.3

Contralat lung

V5 (%)

0.11

0.5

- 3D and 4D CT-based IMRT plans for 10 patients

- delineations on MIP images from 4D-CT

- comparison of target and OARs dosimetry