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Essers et al. Acta Oncol Early Online:1-7. 2014

Breath-hold and volumetric radiation therapy (VMAT)

3D-CRT and VMAT plans for 21 patients on CTs acquired in free-breathing (FB)

and/or in voluntary moderately deep inspiration breath-hold (vmDIBH), D=38.5 Gy

VMAT improves conformity

and delivers lower doses to ipsilateral breast and lung compared to 3D-CRT

vmDIBH

technique results in a

further reduction of ipsilateral lung and heart dose

VMAT increases the contralateral breast dose

3D-CRT

FB

3D-CRT

vmDIBH

VMAT

FB

VMAT

vmDIBH

PTV

V95% 96.4

96.1

98.9

99.1

PTV

CI

1.52

1.47

1.25

1.23

Ipsilat. non-PTV breast

V50% 23.2

23.0

19.7

18.0

Ipsilat. lung

D

mean

(Gy)

3.7

3.4

1.9

1.8

Heart

D

mean

(Gy)

2.0

1.0

1.0

0.6

Contralat. breast

D

max

(Gy)

0.7

0.4

4.6

4.3