1246 / 1674
Ellis
´
NSD model in breast cancer
73 pts
66 pts
NSD identical
Significant worse late reaction using hypofractionation :
skin fibrosis, telangiectasiae, pneumonitis, impared shoulder movement, arm
edema, lung fibrosis, osteonekrosis
Overgaard 1987
median min. target dose 36.7 Gy, 39 days
median min. target dose 41 Gy, 29 days
>3 Gy / fr
2 Gy / fr