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N>600

N>1000

N>360

N=2036

GWAS done in 1850 patients in the RAPPER study (prostate and breast)

The largest GWAS study to date

Documents a true association between common genetic variants and RT

related morbidity

Associations with morbidity appeared to be tumour site-specific, thus different

for breast and prostate

Larger studies are needed, >3000 patients

GWAS and the RAPPER study