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RAPPER

Radiogenomics: Assessment of Polymorphisms for Predicting the Effects of Radiotherapy

N=778 breast cancer patients, 40 Gy / 15 fractions, high risk pts had e- boost 9 Gy

/ 3 fr, some pts had regional RT. Evaluation done on photos from 703 pts

Most scores made on 3-point scale : none/minimal =1, mild =2, marked =3

Follow up: 2 years

This study found no correlation between

late morbidity and any of the almost 100 investigated SNPs