1503 / 1674
N = 1135
Invasive; < 20 mm; N0; G1 or good prognosis subtype
2x2 clinical trial of factorial design:
•
+/- radiotherapy &
•
+/- tamoxifen
Trial entry was allowed to either comparison or both.
Blamey RW, et al. Eur J Cancer. 2013;49:2294-302.
Less local treatment: where is the limit?