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Trial

Age % < 50 <50>

TARGIT

≥ 45 9%

No difference

ELIOT

> 48 7%

No difference

GEC-ESTRO

≥ 40 14%

No difference

Florence University

> 40 16%

No difference

NSABPB- 39 RTOG-413

≥ 18

NA

RAPID

≥ 40 NA

IMPORT LOW

≥ 50 NA

IRMA

≥ 49 ongoing

SHARE

≥50 ongoing

HUNGARIAN

>40

20%

(30-40 years

excluded later on

high LR)