70 / 1674
Ki67/Mib1
-
Expressed in G1 , S , G2 et M
-
Semi-quantitative IHC
-
Prognostic factor
Mib1
⇔
size (+)
grade (+)
mitosis(+)
ER(-)
-
Predictive in neoadjuvant
-
Luminal A vs B, help to CT
decision in ER+ BC
(20% cut-
off)
- …but lack of reproducibility,
especially for intermediate
values 10-30%