984 / 1674
Trial design: Inclusion Criteria
45
•
Breast conservation surgery
±
adjuvant systemic therapy
•
Age ≥50, female
•
Pathological tumour size ≤3cm
•
Invasive unifocal adenocarcinoma
•
Grade I, II or III
•
pN0 or pN1
•
Minimum microscopic margin ≥2mm
Randomised (1:1:1)
N=2018
Whole
N=674
Reduced
N=674
Partial
N=670