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Difference on uncertainty per fraction to uncertainty

f t t l d or o a ose

For normal distributions the number of subsequent

f i

( b i

)

l i

i

f

ract ons o servat ons resu ts n compensat on o

variations

1 / √N

including constant EBRT results in

1 / 2

So 13% per fraction can be 3.5% for total dose